It's safe to use L-Methionine as food additives. However, high doses of L-Methionine can cause brain damage and death.
As L-Methionine is widely known as safe, there is no limit on dosage of intake. However, we still recommend consumers to consult professionals before using large quantity of L-Methionine for long period.
Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
There is no evidence that L-Methionine could have any negative effects on these vulnerable groups. It should be safe to use L-Methionine in food for newborns and pregnant. However, we still recommend consumers to consult professionals before using large quantity of L-Methionine for long period in food for newborns or pregnant.
Generally recognized as safe(GRAS) is a FDA designation that a specific substance or ingredient is generally considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. L-Methionine is considered safe by FDA according to existing data and granted GRAS status.
No breaking news or public health crises reported about L-Methionine reported up to now.
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1. 2-keto-4-(methylthio)butyric acid (keto analog of methionine) is a safe and efficacious precursor of L-methionine in chicks.[J Nutr. 2007 Aug]
Author: Dilger RN, Kobler C, Weckbecker C, Hoehler D, Baker DH.
2. The keto acid of methionine is a safe and efficacious substitute for dietary L-methionine: the answer from chick bioassays.[J Nutr. 2007 Aug]
Author: Stipanuk MH.
3. Treatment of AIDS-associated myelopathy with L-methionine: a placebo-controlled study.[Neurology. 2004 Oct 12]
Author: Di Rocco A, Werner P, Bottiglieri T, Godbold J, Liu M, Tagliati M, Scarano A, Simpson D.
