Vitamin C, CAS# 50-81-7, is a a family of vitamin including ascorbic acid and its salts manufactured through two-step fermentation process, available as White or almost white crystal or crystalline powder. Vitamin C is widely used as antioxidants as it acts as a reducing agent to reverse oxidation in liquids. It is affirmed by US FDA as GRAS(generally recognized as safe) and widely accepted as safe food additive in many countries with E number E300.
No significant side effects reported.
As Vitamin C is widely known as safe, there is no limit on dosage of intake. However, we still recommend consumers to consult professionals before using large quantity of Vitamin C for long period.
Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
There is no evidence that Vitamin C could have any negative effects on these vulnerable groups. It should be safe to use Vitamin C in food for newborns and pregnant. However, we still recommend consumers to consult professionals before using large quantity of Vitamin C for long period in food for newborns or pregnant.
Generally recognized as safe(GRAS) is a FDA designation that a specific substance or ingredient is generally considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Vitamin C is considered safe by FDA according to existing data and granted GRAS status.
No breaking news or public health crises reported about Vitamin C reported up to now.
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1. Pharmacological preconditioning with vitamin C attenuates intestinal injury via the induction of heme oxygenase-1 after hemorrhagic shock in rats.[PLoS One. 2014 Jun 13]
Author: Zhao B, Fei J, Chen Y, Ying YL, Ma L, Song XQ, Wang L, Chen EZ, Mao EQ.
2. The molecular mechanism underlying the proliferating and preconditioning effect of vitamin C on adipose-derived stem cells.[Stem Cells Dev. 2014 Jun 15]
Author: Kim JH, Kim WK, Sung YK, Kwack MH, Song SY, Choi JS, Park SG, Yi T, Lee HJ, Kim DD, Seo HM, Song SU, Sung JH.
3. Efficacy and safety of a new superficial chemical peel using alpha-hydroxy acid, vitamin C and oxygen for melasma.[J Cosmet Laser Ther. 2013 Feb]
Author: Kim WS.
4. Vitamin C inhibits staphylococcus aureus growth and enhances the inhibitory effect of quercetin on growth of Escherichia coli in vitro.[Planta Med. 2012 Nov]
Author: Kallio J, Jaakkola M, Mäki M, Kilpeläinen P, Virtanen V.
